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Estera® Phase II Women's Transitions Formula

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Estera® Phase II — Women's Transitions Formula is Pharmanex's targeted supplement for women in perimenopause — characterized by erratic estrogen fluctuations, declining progesterone, and symptoms including hot flashes, night sweats, mood changes, sleep disruption, and irregular cycles.

NuBodyRx is an authorized Pharmanex and Nu Skin retailer. Every Estera Phase II is 100% authentic, ships fast within the US, and requires no Nu Skin membership.

Key Ingredients

  • Soy isoflavones (genistein, daidzein) — ER-β adaptogenic phytoestrogens: mild estrogenic when estrogen is low, mild anti-estrogenic when high — ideal for the volatile perimenopausal environment
  • Red clover isoflavones (formononetin, biochanin A) — converted to equol for stronger ER-β affinity; supports comfort during hormonal transitions
  • Black cohosh — most clinically studied botanical for menopausal wellness; acts on serotonin and dopamine receptors to support mood and comfort
  • DIM (Diindolylmethane) — promotes healthy estrogen metabolism via 2-OH pathway
  • Flaxseed lignans — adaptogenic phytoestrogens supporting estrogen balance and cardiovascular wellness
  • Chasteberry (Vitex agnus-castus) — supports progesterone balance through dopamine receptor modulation

Primary Benefits

  • Formulated to support comfort during hormonal transitions*
  • Supports restful sleep during hormonal changes*
  • Supports mood stability during hormonal fluctuations*
  • Promotes healthy estrogen metabolism*
  • Supports progesterone balance*
  • Provides phytoestrogen-based skin collagen support*

Who Is Estera Phase II For?

Women who are still menstruating — even if irregularly — and experiencing perimenopausal changes. Typically ages 40–52. If you have gone 12+ consecutive months without a period, transition to Estera Phase III.

Recommended Protocol

Frequently Asked Questions

How is Estera Phase II different from Estera Phase III?

Phase II targets the hormonal volatility of perimenopause — erratic estrogen fluctuations and progesterone changes — with black cohosh, red clover, DIM, and chasteberry. Phase III targets the sustained low-estrogen environment of post-menopause, prioritizing bone density (calcium, D3, K2) and cardiovascular wellness.

How do I know if I should be on Phase II or Phase III?

If you are still menstruating — even irregularly — Estera Phase II is appropriate. If you have gone 12 consecutive months without a period, transition to Estera Phase III. Confirm with your physician.

How long does Estera Phase II take to work?

Most women notice changes in comfort and sleep quality within 4–8 weeks. Adaptogenic phytoestrogen effects develop over 8–12 weeks. Skin collagen support accumulates over 3–6 months.

Can I take Estera Phase II with Beauty Focus Collagen+?

Yes — they are complementary. Estera Phase II provides ER-β-mediated collagen gene activation in fibroblasts; Beauty Focus Collagen+ provides direct fibroblast peptide signaling independent of estrogen receptors. Together they address perimenopausal collagen changes through two synergistic mechanisms.

Is NuBodyRx an authorized Pharmanex retailer?

Yes — NuBodyRx.com is an authorized Nu Skin and Pharmanex retailer. Every Estera Phase II is 100% authentic, backed by the 90-day money-back guarantee, with no membership required.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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