Day + Night Formula
Circadian-aligned science
YGC Targeted
Youth Gene Cluster science
Prysm iO Verified
Track your progress with scanning
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The Science of Day + Night Cellular Renewal
Your cells have a natural rhythm. ageLOC R2 works with it — not against it.
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R2 Day
Targets YGCs related to cellular energy production. Taken in the morning, R2 Day supports your cells' ability to produce and use energy efficiently — so you feel vibrant and alert throughout the day.
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R2 Night
Targets YGCs related to cellular purification and detoxification. Taken in the evening, R2 Night supports your body's natural nighttime cleanup and renewal processes while you sleep.
What ageLOC R2 does for you
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Supports cellular energy production
R2 Day targets the mitochondrial energy YGCs — supporting your cells' ability to generate ATP and feel energized at the cellular level.
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Supports cellular detoxification pathways
R2 Night activates your body's natural cellular cleanup processes — removing waste products and toxins that accumulate during daily life.
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Targets Youth Gene Clusters toward a more youthful state
ageLOC R2 uses Nu Skin's proprietary YGC science to shift gene expression patterns associated with cellular aging back toward a more youthful profile.
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Track the results with Prysm iO
Prysm iO measures your antioxidant levels — a direct marker of cellular health. Use Prysm iO to track how ageLOC R2 is improving your cellular protection over time.
Frequently Asked Questions
How do I take ageLOC R2?
Take R2 Day in the morning and R2 Night in the evening — every day. The timing is designed to align with your body's natural circadian rhythm for maximum cellular benefit.
What is the difference between ageLOC R2 and ageLOC Youth?
ageLOC R2 provides targeted circadian-aligned support for cellular energy (Day) and purification (Night) YGCs. ageLOC Youth provides broader coverage across multiple YGC categories. They work powerfully together as a stack.
Can I use ageLOC R2 with the TR90 system?
Yes — ageLOC R2 is a perfect complement to TR90. R2's cellular energy and purification support helps your body recover and renew throughout the 90-day transformation program.
How does Prysm iO connect to ageLOC R2?
Prysm iO measures your carotenoid antioxidant levels — a key marker of cellular health and protection. As ageLOC R2 improves your cellular function, your Prysm Score reflects the improvement. Scan regularly to track your progress.
Renew your cells. Day and night.
ageLOC R2 works with your body's natural rhythm to support cellular energy and purification around the clock.
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